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    Researcher Profile

    Giovanni Parmigiani, PhD

     
    Giovanni Parmigiani, PhD
     
    Chair, Department of Biostatistics and Computational Biology

    Professor of Biostatistics

    Office phone: 617-632-5323
    Fax: 617-632-2444
    Email: gp@jimmy.harvard.edu

    Preferred contact method: appointment phone
     
     

    450 Brookline Avenue
    CLS 11043
    Boston, MA 02215

    Recent Awards

    • Advising, Mentoring, and Teaching Recognition Award. Johns Hopkins School of Public Health Student Assembly, 2002
    • Edward Rotan Visiting Professorship, M. D. Anderson Cancer Center, 2002
    • Hecht Scholar, 2000
    • Fellow of the American Statistical Association, 1999
    • Myrto Lefkopoulou Distinguished Lecture, Harvard School of Public Health, 1999
    • Savage Ph.D. Thesis Award, 1991
    • Biometrics ENAR Student Travel Award, 1990
    • Gavasakar Dissertation Prize, 1990
    • Graduate Student of the Year, Pittsburgh Chapter of the ASA, 1990
    • Thesis Publication Honor, Universit L. Bocconi, Milano, 1984

    Select Publications

    • Parsons WD, Jones S, Zhang S, Lin JC-H, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu I-M, Gallia G, Olivi A, McLendon R, Rasheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA, Hartigan J, Smith DR, Strausberg RL, Nagahashi Marie SK, Oba Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu V, Kinzler K. An Integrated Genomic Analysis of Glioblastoma Multiforme. Science, 2008 Sep 26;321(5897):1807-12. Epub 2008 Sep 4.
    • Jones S, Zhang S, Parsons WD, Lin JC-H, Leary RJ, Angenendt P, Mankoo P, Carter H, Kamiyama H, Walter K, Nikolskaya T, Nikolsky Y, Hartigan J, Smith DR, Hidalgo M, Leach SD, Klein AP, Jaffee EM, Goggins M, Maitra A, Iacobuzio-Donahue C, Eshleman1 JR, Kern SE, Hruban RH, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu V, Kinzler K. Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses. Science, 2008 Sep 26;321(5897):1801-6. Epub 2008 Sep 4.
    • Leary R, Lin J, Cummins J, Boca S, Wood L, Parsons W, Jones S, Sjblom T, Park BH, Parsons R, Nikolskaya T, Nikolsky Y, Kopelovich L, Papadopoulos N, Pennacchio L,Wang T-L, Markowitz SD, Parmigiani G, Kinzler K, Vogelstein B, Velculescu V. Integrated analysis of homozygous deletions, focal amplifications, and sequence alterations in breast and colorectal cancers. PNAS, October 21, 2008 vol. 105 no. 42 16224-16229.
    • Iversen ES, Parmigiani G, Chen S. Multiple Model Evaluation Absent the Gold Standard via Model Combination. Journal of the American Statistical Association, 103(483):897-909.
    • Kortenhorst MSQ, Zahurak M, Shabbeer S, Kachhap S, Galloway N, Parmigiani G, Verheul HMW, Carducci MA. A Multiple Loop, Double Cube Microarray Design Applied to Prostate Cancer Cell Lines with Variable Sensitivity to Histone Deacetylase Inhibitors. Clinical Cancer Research, 2008 Nov 1;14(21):6886-94.
    • Braun M, Cope L, Parmigiani G. Identifying differential correlations in gene/pathway combinations. BMC Bioinformatics, 2008 Nov 18;9:488.
    • Parmigiani G, Boca S, Lin J, Sjblom T, Kinzler WK, Vogelstein B, Velculescu VE. Design and Analysis Issues in Genome-wide Mutation Analysis Studies of Cancer. Genomics, 2009 Jan;93(1):17-21. Epub 2008 Aug 23.
    • Jones S, Hruban RH, Kamiyama M, Borges M, Zhang X, Parsons DW, Lin JC, Palmisano E, Brune K, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Parmigiani G, Kern SE, Velculescu VE, Kinzler KW, Vogelstein B, Eshleman JR, Goggins M, Klein AP. Exomic sequencing identifies PALB2 as a pancreatic cancer susceptibility gene. Science. 2009 Apr 10;324(5924):217. Epub 2009 Mar 5.
    • Blackford A, Parmigiani G, Kensler TW, Wolfgang C, Jones S, Zhang X, Parsons DW, Lin JC, Leary RJ, Eshleman JR, Goggins M, Jaffee EM, Iacobuzio-Donahue CA, Maitra A, Klein A, Cameron JL, Olino K, Schulick R, Winter J, Vogelstein B, Velculescu VE, Kinzler KW, Hruban RH. Genetic mutations associated with cigarette smoking in pancreatic cancer. Cancer Res. 2009 Apr 15;69(8):3681-8. Epub 2009 Apr 7.
    • Chen S, Blackford AL, Parmigiani G. Tailoring BRCAPRO to Asian-Americans. J Clin Oncol. 2009 Feb 1;27(4):642-3; author reply 643-4. Epub 2008 Dec 15.
    • Lin X, Afsari B, Marchionni L, Cope L, Parmigiani G, Naiman D, Geman D. The ordering of expression among a few genes can provide sample cancer biomarkers and signal BRCA1 mutations. Bioinformatics, 2009; 10:256.
    • Zhou X, Clyde MA, Garrett J, Lourdes V, O'Connell M, Parmigiani G, Turner DJ, Wiles T. Statistical Methods for Automated Drug Susceptibility Testing: Bayesian Minimum Inhibitory Concentration Prediction from Growth Curves. Annals of Applied Statistics, 2009; 3(2):710-730.

    Trainees

    • Ding, Jie, PhD
    • Trippa, Lorenzo, PhD
    • Tyeckucheva, Svitlana, PhD
    • Wang, Xin Victoria, PhD

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