• Researcher Profile

    Suzanne Gaudet, PhD

     
    Suzanne Gaudet, PhD
     
    Assistant Professor of Genetics

    Office phone: 617-632-4269
    Email: Suzanne_Gaudet@dfci.harvard.edu
    Website: The Gaudet Lab

    Preferred contact method: email
     
     

    Research Department

    Cancer Biology

    Area of Research

    TNF

    450 Brookline Avenue
    Smith 836B
    Boston, MA 02215

    Biography

    Suzanne Gaudet obtained her PhD in Biochemistry from Harvard University where she cloned and characterized PDZ-binding kinase, PBK, a mitotic kinase in human cells. She then joined Peter Sorger's laboratory at MIT as a postdoctoral associate for the launch of a project to study how TNF, EGF and insulin affect the cell death decision, using a systems approach. From 2003 to 2008, she worked as a research scientist and scientific coordinator at the Cell Decision Processes Center at MIT and Harvard. She is now assistant professor at the Department Genetics at Harvard Medical School and the Department of Cancer Biology at the Dana-Farber Cancer Insitute. Her research focuses on the quantitative understanding of how TNF-superfamily ligands control cell fate.

    Research

    TNF

    We study TNF-induced fate decisions in mammalian cells. TNF is particularly interesting because it induces both pro-survival and prodeath signals. Combining mathematical modeling and single-cell measurements, we exploit variability in response in a cell population to explore how these signals are integrated in time and space to control cell fate.

    Trainees

    • Lee, Robin
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